Assassin's Creed: Revelations

After the events in the Colosseum Vault which resulted in Lucy Stillman's death, Desmond Miles entered a comatose state and awoke in the Animus' Black Room, following being placed back in the machine by his father, William Miles, and Harlan T. Cunningham. While Shaun Hastings stayed behind in Rome to attend Lucy's funeral, William and Rebecca Crane monitored Desmond's condition while they headed for the city of New York.